CCL2 in Schnitzler syndrome

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منابع مشابه

Schnitzler Syndrome.

A 48-year-old man with typical features of Schnitzler Syndrome is presented, followed by a discussion of the pathogenesis and clinical aspects of this rare disease. Some of the challenges we and others have faced in diagnosing and treating this disease are also discussed. Clinical pearls and pitfalls are emphasized to aid clinicians from varying specialties in recognizing this syndrome and prov...

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The Schnitzler syndrome

The Schnitzler syndrome is a rare and underdiagnosed entity which is considered today as being a paradigm of an acquired/late onset auto-inflammatory disease. It associates a chronic urticarial skin rash, corresponding from the clinico-pathological viewpoint to a neutrophilic urticarial dermatosis, a monoclonal IgM component and at least 2 of the following signs: fever, joint and/or bone pain, ...

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Beyond Urticaria: Schnitzler Syndrome

A 48-year-old male was admitted to our outpatient dermatological clinic complaining of a 2 year-evolution of recurrent urticarial rash and arthralgia on knees and elbows. Physical examination showed evanescent hives in the upper third of the chest and back without associated angioedema (Figure 1a). The patient reported intermittent fever (>38.5 °C) in the outbreaks and swollen neck lymph nodes....

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Urticarial vasculitis and Schnitzler syndrome.

Both urticarial vasculitis and Schnitzler syndrome are serious diseases but a recently gained better understanding of their underlying pathomechanism allows better treatment options than only a decade ago.

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PW03-008 – Mitochondrial disturbances in Schnitzler syndrome

Methods Activity and amount of oxidative phosphorylation complexes (OXPHOS) were analysed by spectrophotometry, histochemistry and imunoelectrophoretic methods in fibroblast cell lines derived from skin biopsies of three adult male patients with Schnitzler syndrome. Ultrastructure of mitochondria, mitochondrial network and reactive oxygen species (ROS) were analysed by fluorescent and electron ...

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ژورنال

عنوان ژورنال: British Journal of Dermatology

سال: 2019

ISSN: 0007-0963,1365-2133

DOI: 10.1111/bjd.17654